10 Comments

Was hoping for a link to coffee enemas. Left disappointed. 1 out of 5

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I have read on the internet that if you replace your morning coffee or tea with green tea you can reduce up to 80% of what little joy you have left in your life.

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I'll raise a cup of fermented beans to that.

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I have a cup of coffee with a coffee chaser. Actually it's like the little old lady who swallowed a fly but with coffee all the way down.

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I always feel like people who recommend cutting caffeine out of your morning and secretly the saddest, angriest, most hate filled bastards in the world and are seeing to spread that hate and sadness by writing these baseless stupid fucking articles.

Anyway, I am off to work in IT, an industry that was built entirely without caffeine, as is well known.

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I envy those people who can have a cup of coffee at 10pm and then punch out a solid 8 hours of sleep.

I'm probably hooked on a long black first thing in the morning not because I need it, and not because it tastes good, but because I'm not a savage and having a hot, caffeinated beverage in the morning is what separates us from beasts.

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Don't be envious. We have ADHD and that's not as much fun as tiktok makes it out to be.

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It's an ADHD thing? For sure, then, I take it back. I had no idea.

I can't do caffeine after 10:30 if I want to sleep at my normal time at night. My affogato has to be decaf.

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I'm one of those and I don't have ADHD. It's a tolerance thing, but then how does it work in the morning?

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From Genetic susceptibility to caffeine intake and metabolism: a systematic review J Transl Med

. 2024 Oct 22;22:961. doi: 10.1186/s12967-024-05737-z "A total of 2552 studies were screened and 26 studies involving 1,851,428 individuals were included. Several genes that were involved with caffeine metabolism such as CYP1A2, ADORA2A, AHR, POR, ABCG2, CYP2A6, PDSS2 and HECTD4 rs2074356 (A allele specific to East Asians and monomorphic in Europeans, Africans and Americans) were associated with habitual caffeine consumption with effect size difference of 3% to 32% in number of cups of caffeinated drink per day per effect allele. In addition, ALDH2 was linked to the Japanese population. Genes associated with caffeine reward included BDNF, SLC6A4, GCKR, MLXIPL and dopaminergic genes such as DRD2 and DAT1 which had around 2–5% effect size difference in number of cups of caffeinated drink for each allele per day".

Hope that clears that up.

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